This question was asked by a participant in our recent webinar on Separation Anxiety:
Q: I am curious as to whether there is ever an increase in the stress levels in the beginning of use of clomipramine for SA or would that be considered a contrary reaction to the meds?
If a patient seems more agitated on ANY medication, I generally discontinue the medication. In some medications group, such as the benzos, increasing the dose may actually help.
In some cases, there can be initial agitation that goes away after a few weeks of treatment. However, I do not continue the medication in those cases. Some of my colleagues do.