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Genetic mapping and DNA

  • VetVine Specialty Consulting Service
    • Moderator
    • 239 posts
     
    June 17, 2015 4:09 PM EDT

    Genetic mapping of certain cancers is ongoing. How far has this gone? Example: the United Health Trust in the U.K. has collected DNA samples from Labradors with malignant melanoma. Has this succeeded in identifying a carrier for this cancer type?

  • Jeffrey Bryan
    • 34 posts
     
    June 17, 2015 5:40 PM EDT

    This remains in its infancy. I cannot find the melanoma data published. There is preliminary data that DNA repair defects may play a role in Golden Retriever lymphomas.  Other breeds (Rottweilers and the gene MET) have been shown to have specific genes or predisposition to osteosarcoma. There is much work yet to be done in this area.