Introduction
NEUROBIOLOGY OF AGING IN THE DOG
Brain Atrophy
Selective Neuron Loss
Senile Plaques (b-Amyloid) in Dogs
Vascular Disorders, Cerebrovascular Amyloid Angiopathy
Tau Neuropathology
Oxidative Damage and Mitochondrial Dysfunction
Correlates of Brain Aging Found in Lysosomal Storage Diseases
NEUROBIOLOGY OF AGING IN THE CAT
Neuron Loss and Atrophy
Ab
Tau Phosphorylation
Neuronal Loss in Feline Niemann-Pick Type C Disease and Similarities to AD
CLINICAL IMPLICATIONS OF BRAIN AGING IN DOGS AND CATS
SUMMARY
Acknowledgments
References